Language Neuroscience Laboratory

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ASHA Research Symposium

I will present some of our recent work as part of the 2018 ASHA Research Symposium ‘Advances in Neuroplasticity Research: Language Recovery in Aphasia’.


Workstation

Vintage IBM keyboard molded from Toblerone (among other features)...


Society for the Neurobiology of Language, Quebec City, 2018


An adaptive semantic matching paradigm for reliable and valid language mapping in individuals with aphasia

We describe an adaptive semantic matching paradigm and demonstrate that it is a feasible, reliable and valid method for mapping language regions in people with aphasia.

Wilson SM, Yen M, Eriksson DK. An adaptive semantic matching paradigm for reliable and valid language mapping in individuals with aphasia. Hum Brain Mapp 2018; 39: 3285-307. [pdf]


Neural representation of vowel formants in tonotopic auditory cortex

Cortical encoding of vowels is scaffolded on tonotopy, a fundamental organizing principle of auditory cortex that is not language-specific.

Fisher JM, Dick FK, Levy DF, Wilson SM. Neural representation of vowel formants in tonotopic auditory cortex. NeuroImage 2018; 178: 574-82. [pdf]


Selective interference with syntactic encoding during sentence production by direct electrocortical stimulation of the inferior frontal gyrus

Direct cortical stimulation of the left inferior frontal gyrus can interfere with syntactic encoding but not single word processing, suggesting that this region plays an important role in the encoding of syntactic structure during sentence production.

Chang EF, Kurteff G, Wilson SM. Selective interference with syntactic encoding during sentence production by direct electrocortical stimulation of the inferior frontal gyrus. J Cogn Neurosci 2018; 30: 411-20. [pdf]


A quick aphasia battery for efficient, reliable, and multidimensional assessment of language function

The Quick Aphasia Battery (QAB) aims to provide a reliable and multidimensional assessment of language function in about a quarter of an hour, bridging the gap between comprehensive batteries and rapid screening instruments.

Wilson SM, Eriksson DK, Schneck SM, Lucanie JM. A quick aphasia battery for efficient, reliable, and multidimensional assessment of language function. PLOS ONE 2018; 13(2): e0192773. [pdf]


New paper


Society for the Neurobiology of Language, Baltimore, 2017


My brain in the form of chocolates

An amazing birthday gift from my lab members! Probably not the intended use of Vanderbilt’s 3D printer...


Wernicke’s model of language

Credit: Deborah Levy.


New papers

 

 


MRI cake

An MRI cake for my birthday! Thank you, Deb, Melodie, Sarah and Jillian for the impromptu party...


New paper

This paper, based on Stephanie Yagata's Masters thesis, comprises a detailed investigation of early patterns of change in connected speech after focal infarction of Wernicke's area.


New paper


Moving to Vanderbilt University

The lab has now relocated to the Department of Hearing and Speech Sciences at Vanderbilt University Medical Center.


Congratulations, graduates of 2016

Angelica McCarron, B.S., Stefanie Lauderdale, B.S.


New paper

This paper is based on Alexa's honors thesis, for which she received the award for Excellence in Undergraduate Research from the Department of Speech, Language, and Hearing Sciences for 2015.


New paper


Congratulations class of 2015


Wernicke's model of language

Credits: Angelica McCarron, Alexa Bautista.


Making posters for UBRP conference


Farewell, Temre


New paper


Angelica on the radio

Angelica McCarron appeared on KXCI's "The Thesis" today, where she talked about the neural basis of language, explained her three projects, and did some guest DJing. Listen!


Our research in UA News

NIH Awards UA $2M to Study Recovery of Language After Stroke


Congratulations, Temre!

Temre Brandt has received the award for Excellence in Undergraduate Research from the Department of Speech, Language, and Hearing Sciences for 2014. This award is in recognition in the critical roles she is played in both our acute stroke project and our inflectional morphology in PPA project.


Congratulations, Julia!

Julia Fisher has received a GPSC Achievement Award for Outstanding Interdisciplinary Development by a Graduate/Professional Student (Honorable Mention), for her work bridging Lingusitics and Speech, Language, and Hearing Sciences.


Wernicke's model of language

Credits: Lauren Zimmerman, Gina Miller, Betsy Lukins.


New paper

Here is a map of core language areas in an individual participant, using our new Siemens Skyra 3T scanner, tiny voxels, hypercapnic normalization, and vein masking. Note the precise localization of language regions to the dorsal bank of the superior temporal sulcus!

This research is described in our new paper which is now available online ahead of print:


Tucson sunrise


Monsoon

It's been a subpar monsoon season for central Tucson, but anyone that got caught out in this today got properly wet!


Scanner console room

After a few months of making do with surpus furniture that Scott, Julia and I pieced together, we now have proper furniture in the scanner console room! Lots of fun unplugging 6,000 cords and then trying to remember how to reassemble everything...


Scanner building

They painted the scanner building desert colors...


Brain cake

Credits: Milo White, Samantha Ricks.


New paper


Sabino Canyon


Wernicke's model of language

Credits: Temre Brandt, Rachel Auer, Chelsey Salli, Natalie Carmen, Alex Swiderski.


Research Skyra


New version of VLSM

I've just uploaded a new version of VLSM: version 2.5 to the Resources page. The new version allows lesion size to be automatically calculated and included as a covariate. To use this feature, simply include 'LesionSize' in your list of variables. This is useful only for analysis of discrete lesions, not for VBM.


Pavlova Brain


New paper


Mount Wrightson


New clinical scanner

The new clinical 3 Tesla Skyra is being installed at the medical center... very exciting!


Pima Canyon


New version of VLSM

I've just uploaded a new version of VLSM: version 2.4 to the Resources page. The main development is that an extra text file (roi.txt) with subject-by-subject lesion data for each cluster is now included in the output directory, to facilitate post-hoc analyses such as multiple regression.


New scanner

It may not look like much, but this is the new research MRI facility at the University of Arizona. The walkway was just poured today! Construction is on track for the new Siemens 3T Skyra scanner to be up and runnning in early 2013...


Collaborators

After Borna's Neurology grand rounds presentation...


New paper


Class fMRI project

Our "Cognitive Neuroscience of Language" class ran an experiment using noise vocoded speech to look at the neural correlates of language intelligibility and effortful speech recognition. Kat "Nico" Carbonell came up with the idea for the study, and Andrew DeMarco prepared the psychtoolbox script. Julia Fisher (pictured below) provided the brain.


Congratulations to lab members past and present

Ashley Chavez and Lisa Wilson have been accepted to top masters programs in Speech-Language Pathology. Matt Stib has been accepted to a top medical school. Congratulations to all!


The Wernicke-Lichtheim model in cake form

Janette McGuire created this delicious and anatomically accurate depiction of the Wernicke-Lichtheim model.


Ashley Chavez receives WAESO funding for her project "Language deficits after neurosurgery"

Our proposal has been funded by the Western Alliance to Expand Student Opportunities (WAESO). Congratulations Ashley.